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CDC, ATSDR

Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

See also our compilation of other Databases and Resources

For questions or comments about the database, please contact us through our Contact form.

beryllium

CAS number: 7440-41-7

Diseases linked to this toxicant    Grouped by strength of evidence

Strong Evidence

Berylliosis

Chronic renal disease

Lung cancer

Pneumonitis (hypersensitivity)

Renal stones

Skin ulceration

Good Evidence

Bronchitis - acute

Granulomatous disease (liver)

Nasal septal perforation

Pneumonia

Pulmonary edema

Pulmonary fibrosis

Limited Evidence

Bone cancer/Ewings sarcoma

Cardiomyopathy

Immune suppression

Mesothelioma

Sarcoidosis

Seizures

NOTE: The toxicant–disease relationships  shown above were last updated in 2011. The relationships shown here are still valid, but additional research has been conducted since that time. Additional research on this toxicant can be found at this link:

COMPARATIVE TOXICOGENOMICS DATABASE: CURATED RESULTS

This link will direct your search to an external database, the Comparative Toxicogenomics Database (CTD). This database is different from, and complementary to, our database.

More information about sources and methods

  • CHE’s Toxicant and Disease Database evaluates existing evidence and categorizes that evidence based on its strength. It is constructed using expert judgment and epidemiological causal inference.
  • The CTD, in contrast, is a continually updated resource that presents information on a broad range of literature on chemical-disease relationships. It also provides data on genes, biological processes, and phenotypes related to chemicals and diseases. It does not categorize information based on strength of evidence,  include an expert judgment process, or draw causal conclusions about toxicant-disease relationships.
  • The link we have provided on this page goes directly to CTD's curated results, which are a subset of the information available through CTD. Curated results in CTD are those for which studies are available on the toxicant-disease relationship.

References for our 2011 disease list

Carpenter DO, Arcaro K, Spink DC. Understanding the human health effects of chemical mixtures. Environmental Health Perspectives. 2002;110(suppl 1):25-42.

Gottschall EB. Occupational and environmental thoracic malignancies. Journal of Thoracic Imaging. 2002 Jul; 17:189-197.

International Agency for Research on Cancer (IARC). Agents Classified by the IARC Monographs. Accessed in 2010.

Kelleher P, Pacheco K, Newman LS. Inorganic dust pneumonias: the metal-related parenchymal disorders. Environmental Health Perspectives. 2000 Aug;108 Suppl 4:685-96.

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill 2001.

LaDou J, Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.

Leikin JB, Davis A et al. Selected topics related to occupational exposures. Part IV. Occupational liver disease. Disease-a-Month. 2000 Apr;46(4):296-310.

Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.