Toxicant and Disease Database
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The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.
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Asthma - allergen, sensitizer
Causes Grouped by strength of evidence
Strong Evidence | Good Evidence | Limited Evidence |
Notes
Allergens causing allergic asthma can also cause allergic rhinitis. Over 250 agents have been documented to cause immunological occupational asthma, a few broad categories are included here. The haplotype HLA DQB1*0503 is associated with TDI asthma, while allele DQB1*0501 confers protection to TDI. The Th2 type of T helper cells has been associated with an increased likelihood of developing allergies and asthma. Air pollutants may act in conjunction with common allergens to increase sensitivity to other common allergens.