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CDC, ATSDR

Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

See also our compilation of other Databases and Resources

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Autoimmune antibodies (positive ANA, anti-DNA, RF, etc.)

Causes    Grouped by strength of evidence

Strong Evidence

silica

Good Evidence

1,1,1-trichloroethane

asbestos

benzene

carbon tetrachloride

formaldehyde

mercury

solvents

trichloroethylene (TCE)

Limited Evidence

cadmium

carbamates

chlordane

chlorpyrifos

chromium

copper

gold

heptachlor

hexachlorobenzene

lithium

organochlorine pesticides

pentachlorophenol (PCP)

pesticides

phenoxyacetic herbicides

pyrethins / pyrethroids

silicone / parafin breast implants

UV radiation

vinyl chloride

Notes

Although the presence of auto-antibodies is a part of the diagnosis of autoimmune disease, the relevance of auto-antibodies in otherwise health individuals is unknown. Mercury-induced autoimmunity has a strong genetic component. Some strains of rats are completely resistant while others are exquisitely sensitive to mercury toxicity. Susceptibility has been linked to MHC and non-MHC genes.