Toxicant and Disease Database

The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and or toxicants can be viewed by utilizing the search options below. See a full description of the database and our methodology.

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Select one of the following

Select a Disease Category

Select a Disease

Select a Toxicant

Search by CAS number

Search by disease keyword

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Cranio-facial malformations*

Causes Grouped by strength of evidence

Strong Evidence ethyl alcohol (ethanol) toluene	Good Evidence ethylene glycol ethers ionizing radiation mercury PCBs (polychlorinated biphenyls), not otherwise specified solvents	Limited Evidence cadmium carbon disulfide cyanazine lead methylazoxymethanol acetate organophosphate pesticides tetrachloroethylene (PCE)

Notes

*Includes microcephaly, macrocephaly, gingival hyperplasia, wide saggital suture, facial edema, and exophthalmos.

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Human environmental disease network: a computational model to assess toxicology of contaminants

About This Database

See a description of database methods, definitions and limitations.

Information in this database was originally drawn from these texts:

Klaassen CD, Ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th Edition. New York: McGraw-Hill, 2001.
LaDou J. Ed. Occupational and Environmental Medicine, 3rd Edition. New York: Lange Medical/McGraw-Hill Company, 2004.
Rom WM. Environmental and Occupational Medicine, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins Publishers, 1998.

Further references are or will be posted with the displays of individual toxicants.

Toxicant and Disease Database

Cranio-facial malformations*

Notes

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About This Database